Prochlorperazine Edisylate Injection 5 mg per mL Multiple-Dose Vials 2 mL x 10/Pack (RX)

Prochlorperazine Edisylate Injection 5 mg/mL by Caplin Steriles USA is a sterile, Multiple-Dose parenteral solution, expertly formulated for rapid and controlled management of severe nausea, vomiting, and psychotic disorders. Provided in convenient 2 mL vials (10 vials per pack), this trusted medication is widely used in hospitals, clinics, and emergency settings for fast symptom relief when oral administration is not possible or appropriate.

What is It Used For?

Prochlorperazine Edisylate Injection is primarily indicated for:

• Control of severe nausea and vomiting (due to surgery, chemotherapy, radiation, or underlying illnesses)
• Management of Schizophrenia and Severe Psychotic Disorders
• Short-term treatment of nonpsychotic anxiety (as prescribed by a physician)

Details & Product Features

• Active Ingredient: Prochlorperazine Edisylate 5 mg per mL
• Pack Size: 2 mL vials; 10 vials per box
• Sterile Multiple-Dose Vials: Ideal for controlled hospital/clinical use
• Route of Administration: Intramuscular (IM) or Intravenous (IV) injection
• Preservative added for multiple dosing
• Manufactured by Caplin Steriles USA: Renowned for pharmaceutical quality and reliability
• Latex-free packaging

Directions for Use

1. Administration: For IM or IV use only. Must be administered by a trained healthcare professional.
2. Preparation: Inspect vial for clarity and particulate matter. Use aseptic technique.
3. Dosage adjustment: According to age, indication, severity, and patient response.
4. Discard unused portion as per institutional protocols.

Note: Never use in patients with known hypersensitivity to phenothiazines.

Dosage

Nausea and Vomiting (Adults):

• Typical dose: 5–10 mg IM or IV every 3–4 hours as needed.
• Maximum: Do not exceed 40 mg daily.

Psychotic Disorders (Adults):

• Dose varies: Typically 10–20 mg deep IM, repeated every 2–4 hours as prescribed.
• Transition to oral therapy as soon as feasible.

Geriatric Patients: Start at lower dosages; monitor closely for side effects.

Pediatric Use: Not recommended in children under 2 years or <9 kg. Use only per physician’s order.

Always follow the exact dosage regimen as prescribed by your healthcare provider.

CDC Guidelines & Best Practices

• The CDC recognizes prochlorperazine as a supportive antiemetic for nausea and vomiting related to chemotherapy, radiation, and post-operative care.
• Safe use protocols: Medical supervision, minimal effective dose, and monitoring for CNS or extrapyramidal side effects.
• Always follow local and hospital guidelines for injectable antiemetics and antipsychotics.

Warnings & Precautions

• CNS Depression: Can cause sedation and impair mental/physical abilities.
• Extrapyramidal Reactions: May cause dystonia, tardive dyskinesia, parkinsonism.
• Neuroleptic Malignant Syndrome: Rare but life-threatening – discontinue if symptoms develop.
• Hypotension/Risk of falls: Monitor cardiovascular status, especially in elderly.
• QT Prolongation: Use with caution in patients with known cardiac history.
• Use in Pregnancy/Lactation: Not recommended unless clearly needed.
• Contraindications: Known phenothiazine hypersensitivity, coma, severe CNS depression, bone marrow depression, children <2 years (or <9 kg).

Possible Side Effects

Common side effects:

• Drowsiness
• Blurred vision
• Dizziness or hypotension
• Dry mouth
• Constipation

Serious side effects (seek immediate medical attention):

• Extrapyramidal symptoms: tremor, muscle stiffness, restlessness, involuntary movements
• Neuroleptic Malignant Syndrome: high fever, altered consciousness, muscle rigidity
• Allergic reactions: rash, swelling, breathing difficulties
• Jaundice or other signs of liver dysfunction
• Seizures or severe confusion

Promptly report any serious side effects to a healthcare professional.

Important Safety Information

• For institutional or prescription use only. Not for self-administration.
• Keep out of reach of children.
• Not for use in pediatric patients under 2 years old.
• Use only as directed by a licensed healthcare provider.
• Discard any unused medication after the recommended period.

Prochlorperazine Edisylate Injection 5 mg/mL by Caplin Steriles USA – Trusted efficacy in hospital-grade nausea, vomiting, and psychosis management.