Sodium Bicarbonate Injection 8.4% Hospira 50 mL Vials 25/pack (Rx)

Hospira Sodium Bicarbonate for Injection 8.4% is a sterile, non-pyrogenic solution formulated for intravenous use in clinical and hospital settings. Each 50 mL vial contains sodium bicarbonate at a concentration of 8.4% (1 mEq/mL), designed to correct metabolic acidosis and treat medical emergencies that require rapid pH regulation. Supplied by Pfizer Injectables, this trusted product comes in a pack of 25 convenient single-use vials for consistent dosing and sterility.

What It Is Used For

Hospira Sodium Bicarbonate for Injection 8.4% is primarily indicated for:

• Treatment of Metabolic Acidosis: Including conditions associated with severe renal disease, uncontrolled diabetes, cardiac arrest, lactic acidosis, and certain drug intoxications.
• Cardiac Arrest: As an adjunct therapy to correct severe acidosis during resuscitation.
• Urine Alkalinization: To increase the elimination of certain drugs and toxins.
• Correction of Hyperkalemia: By promoting cellular uptake of potassium.
• Drug Vesicant Neutralization: As a neutralizing agent for certain injected medications.

Details & Features

• Concentration: 8.4% Sodium Bicarbonate (1 mEq/mL)
• Volume: 50 mL per vial
• Packaging: 25 single-dose vials per box
• Sterile & Non-Pyrogenic: Ideal for IV administration
• Latex-Free Packaging: Reduces risk of allergic reactions
• Transparent, Colorless Solution: Allows for easy inspection prior to administration
• Ready-to-Use: No dilution required for most adult dosing scenarios
• Trusted Manufacturer: Pfizer Injectables ensures quality and consistency

Directions

1. Inspection: Ensure that the solution is clear and vial is undamaged before use.
2. Aseptic Technique: Use sterile equipment and procedures during preparation and administration.
3. Administration: Administer by slow intravenous injection or infusion under the supervision of a healthcare professional. Follow specific protocols for emergency interventions or in combination therapy as directed by a physician.
4. Discard Unused Portion: Single-use vials; discard any remaining solution after initial use.

Dosage

• Individualized Dosage: Dosage must be calculated based on the patient's clinical condition, lab results, and physician’s instructions. A typical adult dose for acidosis may range from 1 to 2 mEq/kg, administered slowly IV.
• Pediatric Dose: Carefully calculated by a physician according to patient needs.
• Infusion Rates: IV administration should be slow and closely monitored, especially in children and the elderly.

Always consult official prescribing information and a healthcare provider for precise dosing guidelines tailored to each patient.

Allergies

• Hypersensitivity: Not common, but inform your healthcare provider if you have allergies to sodium bicarbonate or any ingredients in the product.
• Latex-Free: Packaging is free from latex to minimize risk of allergic reactions.

Drug Interactions

• Potential Interactions:
  • Cardiac Glycosides (e.g., Digoxin): Increased risk of toxicity due to elevated pH.
  • Corticosteroids or Corticotropin: May elevate sodium retention.
  • Tetracyclines, Methenamine Compounds: Decreased effectiveness or altered drug metabolism.
  • Concurrent Infusions: Monitor pH and compatibility with other IV solutions or medications.

Review all medications with your healthcare provider or pharmacist before use.

Side Effects or Warnings

Side Effects

• Local Reactions: Pain, redness, or inflammation at the injection site
• Systemic Effects: Metabolic alkalosis, hypernatremia (high sodium), hypokalemia (low potassium), tetany, muscle twitching, or seizures with overdose or rapid administration
• Fluid Overload: Especially in patients with compromised cardiac or renal function

Warnings

• For Intravenous Use Only: Never administer intra-arterially or intramuscularly.
• Avoid Overcorrection: Administer cautiously to avoid serious metabolic imbalance.
• Close Monitoring Required: Frequent monitoring of blood gases, electrolytes, and patient clinical status is mandatory.
• Special Populations: Use with caution in children, elderly, or those with renal/cardiac dysfunction or hypertension.
• Pregnancy & Nursing: Use only if clearly needed and prescribed by a physician.

Storage

• Store at Controlled Room Temperature (20°-25°C/68°-77°F)
• Do not freeze. Discard if solution is cloudy, discolored, or contains particulates.

Hospira Sodium Bicarbonate for Injection 8.4% by Pfizer Injectables is trusted by hospitals, clinics, and emergency settings worldwide for rapid, effective acid-base management. Choose quality and reliability for critical patient care – order today for prompt supply and exceptional performance!