Albutein 25% (Human) Albumin Single-Dose Vial Preservative-free 100 mL (RX)

Albutein 25% (Human) Albumin is used to treat a variety of medical conditions related to low blood volume and protein deficiency. It is often used in cases of hypovolemia, severe burns, shock, and hypoalbuminemia. This solution helps restore blood volume, maintain cardiac output, and support tissue perfusion. Derived from human plasma, Albutein 25% aids in re-establishing normal osmotic balance and is administered intravenously by healthcare professionals to ensure proper dosage and monitoring.

Introducing Albutein 25% (Human) Albumin Single-Dose Vial, a high-concentration, preservative-free solution meticulously crafted by Grifols Therapeutics to restore and maintain plasma volume in patients with low blood albumin levels. Derived from human plasma, this medical-grade albumin solution is ideal for addressing hypovolemia, hypoalbuminemia, and as a supportive treatment in a variety of medical conditions such as acute liver failure and in surgical settings. Packaged in convenient 100 mL single-dose vials, Albutein 25% provides a reliable and effective means of ensuring patient stability and recovery, backed by Grifols' commitment to safety and quality.

Details and Features:

• Concentration and Composition: Contains 25 g of human albumin per 100 mL (25% solution), free of preservatives for enhanced safety.
  
• Packaging: 100 mL single-dose vials designed for easy handling and precise dosage.
  
• Source: Purified from pooled human plasma, adhering to rigorous screening and testing protocols. Purified from pooled human plasma, adhering to rigorous screening and testing protocols.
  
• Applications: Effective for hypovolemia, hypoalbuminemia, and supporting hemodynamic stability in acute conditions.
  
• Quality Assurance: Developed by Grifols, a leader in plasma-derived therapies, ensuring high purity and safety.
  
• Storage: Maintain at controlled room temperature; do not freeze.

Mechanism of Action:

Albutein 25% works primarily by restoring and stabilizing plasma volume due to its colloid osmotic properties. Albumin, the principal protein constituent of human plasma, serves multiple physiological roles including maintaining oncotic pressure, binding and transporting hormones, enzymes, and drugs. By increasing blood plasma volume, Albutein effectively counteracts hypovolemia, supports circulation, and stabilizes hemodynamic parameters, thus facilitating improved oxygen and nutrient delivery to tissues.

Directions for Use:

1. Preparation: Inspect the vial for particulate matter and discoloration before use. Do not use if the solution is cloudy or contains precipitates.
2. Dosage and Administration: Administer intravenously. Dosage should be individualized based on patient condition and response to treatment. Typically used in conditions requiring rapid volume expansion or albumin replacement.
3. Administration Rate: Infuse at a rate that is appropriate for the patient's cardiovascular status, monitored by a healthcare professional.

Warnings:

• Hypersensitivity Reactions: Monitor for allergic or anaphylactic reactions; immediately discontinue use if symptoms occur.
  
• Cardiac and Pulmonary Function: Caution in patients with conditions such as heart failure, severe anemia, or renal impairment to prevent circulatory overload.
  
• Hemodynamic Monitoring: Careful attention to hemodynamic parameters is essential to avoid complications related to volume overload.
  Infection Risk: Ensure sterility in administration to mitigate infection risk.

Side Effects:

Though generally safe, Albutein 25% may cause side effects, including:

• Common Side Effects: Mild fever, chills, or rash following infusion.
  
• Serious Side Effects: Rapid changes in blood pressure, signs of allergic reaction (hives, anaphylaxis), or fluid overload leading to pulmonary edema.
  
• Monitoring Required: Ongoing monitoring of cardiovascular status and fluid balance is recommended during therapy.

Albutein 25% (Human) Albumin Single-Dose Vial by Grifols Therapeutics represents an essential tool in restoring plasma volume and supporting patient recovery during critical care situations. Its use should be guided by experienced healthcare providers to achieve optimal outcomes and the highest standard of patient care.