{"product_id":"vincristine-sulfate-injection-1-mg-single-dose-vial-2-ml-pfizer","title":"Vincristine Sulfate Injection 1 mg Single-dose Vial 2 mL by Pfizer (RX)","description":"\u003cp\u003eVincristine Sulfate Injection is a chemotherapeutic medication used primarily to treat various types of cancer, including leukemia, lymphoma, and certain types of solid tumors. It functions by inhibiting the growth of cancer cells, thereby preventing their spread in the body. As a vinca alkaloid, it is administered intravenously under medical supervision and is often part of a combination chemotherapy regimen. Due to its potent effects, Vincristine can have significant side effects, thus requiring careful monitoring during treatment.\u003c\/p\u003e\n\u003cp\u003eVincristine Sulfate Injection is a chemotherapy medication provided by Pfizer Injectables in a 1 mg single-dose vial of 2 mL solution. It is used in the treatment of various types of cancer, including leukemia, lymphoma, and other types of tumors. This injectable form is intended for intravenous administration and is typically part of a combination chemotherapy regimen.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDetails and Features\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eActive Ingredient:\u003c\/strong\u003e Vincristine Sulfate\u003cbr\u003e\u003cstrong\u003eConcentration: \u003c\/strong\u003e1 mg per 2 mL vial\u003cbr\u003e\u003cstrong\u003eFormulation:\u003c\/strong\u003e Injectable solution for intravenous use\u003cbr\u003e\u003cstrong\u003eIndication:\u003c\/strong\u003e Used in the treatment of leukemia, Hodgkin's lymphoma, non-Hodgkin's lymphoma, neuroblastoma, rhabdomyosarcoma, and other types of cancer\u003cbr\u003e\u003cstrong\u003eAdministration:\u003c\/strong\u003e Administered via intravenous injection by a healthcare professional in a clinical setting\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanism of Action\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVincristine is a vinca alkaloid that exerts its effects by inhibiting microtubule formation in the mitotic spindle of dividing cells. This interruption in microtubule dynamics inhibits cell division, thereby leading to cell death. Its action is specific to the M phase (mitosis) of the cell cycle, making it effective against rapidly dividing cancer cells.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eExtravasation Risk:\u003c\/strong\u003e Care must be taken to avoid extravasation during administration, as vincristine is a vesicant that can cause significant tissue damage.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuropathy:\u003c\/strong\u003e Vincristine can cause peripheral neuropathy, resulting in numbness, tingling, or pain, primarily in the hands and feet.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBone Marrow Suppression: \u003c\/strong\u003eMay result in a lower count of white blood cells, red blood cells, and platelets, which could increase the risk of infection, anemia, and bleeding.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContraindications: Patients\u003c\/strong\u003e with demyelinating form of Charcot-Marie-Tooth syndrome should not receive vincristine.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePregnancy and Breastfeeding:\u003c\/strong\u003e Not recommended due to potential harm to the fetus or infant.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eSide Effects\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eWhile vincristine is effective, it is associated with several potential side effects, some of which can be serious:\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCommon Side Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eConstipation\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eNausea and vomiting\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eFatigue\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eHair loss (alopecia)\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eLoss of appetite (anorexia)\u003cbr\u003e  \u003cbr\u003e\u003cstrong\u003eSerious Side Effects:\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePeripheral neuropathy\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eSevere constipation and intestinal obstructions\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eAltered mental status\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eHepatotoxicity (liver damage)\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eSevere dehydration\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eOther Considerations:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePatients may experience jaw pain, joint pain or muscle weakness.\u003cbr\u003eMonitoring of blood counts and liver function tests is required to watch for adverse effects.\u003cbr\u003e  \u003cbr\u003ePatients receiving Vincristine Sulfate Injection should be under the care of a healthcare professional experienced in the use of cancer chemotherapeutic agents. Any serious adverse effects should be reported to a healthcare provider immediately. Depending on tolerability and response, dose adjustments may be necessary.\u003c\/p\u003e","brand":"Pfizer Injectables","offers":[{"title":"Default Title","offer_id":53337909559614,"sku":"61703-0309-16","price":2650.99,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0872\/3408\/5182\/files\/Vincristine-Sulfate-Injection-1-mg-by-Pfizer.jpg?v=1776780558","url":"https:\/\/himkhand.com\/products\/vincristine-sulfate-injection-1-mg-single-dose-vial-2-ml-pfizer","provider":"Himkhand","version":"1.0","type":"link"}