{"product_id":"pfizer-vancomycin-hydrochloride-for-injection-single-dose-add-vantage-vials-1-gram-10-box","title":"Vancomycin Injection 1 Gram ADD-Vantage Vials, 10\/Box by Pfizer (Rx)","description":"\u003cp\u003eVancomycin Hydrochloride 1 Gram Injection is an antibiotic used to treat serious bacterial infections, particularly those caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and other resistant strains. It is often administered intravenously for infections such as pneumonia, septicemia, skin infections, and endocarditis. Vancomycin works by inhibiting cell wall synthesis, ultimately killing the bacteria. It is crucial in clinical settings where standard antibiotics are ineffective.\u003c\/p\u003e\n\u003cp\u003eVancomycin Hydrochloride Injection is a glycopeptide antibiotic used to treat serious or severe infections caused by gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and other infections where other antibiotics are ineffective. The formulation is provided by Pfizer Injectables in the form of 1-gram ADD-Vantage vials, which are designed for reconstitution and immediate attachment to an IV bag. This packaging offers convenience for healthcare providers in hospital settings, ensuring timely preparation and administration.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDetails and Features\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eActive Ingredient: Vancomycin Hydrochloride\u003cbr\u003eDosage Form: Powder for injection\u003cbr\u003eStrength: 1 gram per vial\u003cbr\u003ePackaging: 10 ADD-Vantage vials per box\u003cbr\u003eUsage: Designed for intravenous administration after reconstitution\u003cbr\u003eManufacturer: Pfizer Injectables\u003cbr\u003ePurpose: Treatment of serious gram-positive bacterial infections, especially in hospitalized patients\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanism of Action\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVancomycin works by inhibiting bacterial cell wall synthesis. It binds specifically to the D-alanyl-D-alanine terminus of cell wall precursor units, blocking the action of enzymes involved in forming peptidoglycan structures critical for bacterial cell walls. This disrupts cell wall integrity, causing bacterial cell death, especially in cases of gram-positive bacteria that are resistant to other antibiotics.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOtotoxicity:\u003c\/strong\u003e Vancomycin has the potential to cause hearing loss, particularly in patients with pre-existing hearing issues or those who receive high doses. Routine auditory testing is advised for patients at risk.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNephrotoxicity: \u003c\/strong\u003eThere is a risk of kidney damage, especially when administered concomitantly with other nephrotoxic drugs. Monitor renal function regularly.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInfusion Reactions: \u003c\/strong\u003eRapid infusion can lead to \"red man syndrome,\" a condition characterized by flushing, rash, and sometimes hypotension. This is mitigated by slower infusion rates (over at least 60 minutes).\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interactions:\u003c\/strong\u003e Use caution in patients taking other nephrotoxic or ototoxic agents.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecific Populations:\u003c\/strong\u003e Dose adjustments may be needed for elderly patients or those with renal impairment due to altered pharmacokinetics.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eSide Effects\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCommon Side Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRed or flushed skin (\"red man syndrome\")\u003c\/li\u003e\n\u003cli\u003eInjection site pain or inflammation\u003c\/li\u003e\n\u003cli\u003eMild rash or allergic reactions\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSerious Side Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHearing loss or tinnitus\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eSignificant renal impairment or acute kidney injury\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eSevere allergic reactions: Difficulty breathing, swelling of the face or throat\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eNeutropenia or other blood-related issues with prolonged use\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdministration and Monitoring\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVancomycin Hydrochloride should be administered intravenously, typically over a period of at least 60 minutes to avoid reactions associated with rapid infusion. Healthcare providers should monitor patients' kidney function and auditory function, particularly for therapies extending beyond the typical course or in at-risk patients. Blood levels of vancomycin can be measured to ensure therapeutic yet non-toxic concentrations, facilitating appropriate dose adjustments. Proper aseptic techniques should be used during preparation and reconstitution, adhering to all guidelines for safe compounding and administration.\u003cbr\u003e\u003c\/p\u003e","brand":"Pfizer Injectables","offers":[{"title":"Default Title","offer_id":53337903825214,"sku":"00409-6535-01","price":16733.99,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0872\/3408\/5182\/files\/PfizerVancomycinHydrochlorideforInjectionSingle-doseADD-VantageVials1Gram.jpg?v=1776780361","url":"https:\/\/himkhand.com\/products\/pfizer-vancomycin-hydrochloride-for-injection-single-dose-add-vantage-vials-1-gram-10-box","provider":"Himkhand","version":"1.0","type":"link"}