{"product_id":"lidocaine-hcl-1-and-epinephrine-1-1-100-000-for-injection-30-ml-multiple-dose-25-pack","title":"Lidocaine 1% with Epinephrine 1% 1:100,000 Inj 30 mL Multiple Dose, 25\/Pack (Rx)  Exp : August 2026","description":"\u003cp\u003eLidocaine 1% with Epinephrine 1:100,000 for Injection is used as a local anesthetic to provide pain relief and reduce bleeding during surgical, medical, and dental procedures. Lidocaine works by blocking nerve signals to numb the treatment area, while epinephrine acts as a vasoconstrictor, narrowing blood vessels to prolong the anesthetic effect and minimize bleeding. This combination is ideal for procedures requiring effective and lasting anesthesia with improved surgical field visibility, enhancing precision and patient comfort during the intervention.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline; color: rgb(255, 42, 0);\"\u003e\u003cem\u003e\u003cstrong\u003eCurrent Expiration from Manufacture : August 2026\u003c\/strong\u003e\u003c\/em\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eLidocaine 1% with Epinephrine 1:100,000 Injection is a sterile solution used for local or regional anesthesia in various surgical and dental procedures. The combination includes lidocaine hydrochloride, a local anesthetic, and epinephrine, a vasoconstrictor. This formulation is provided in 30 mL multiple-dose vials, with each pack containing 25 vials. The addition of epinephrine helps to prolong the anesthetic effect and reduce local bleeding.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDetails and Features:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVolume:\u003c\/strong\u003e 30 mL per vial\u003cbr\u003e\u003cstrong\u003ePackaging: \u003c\/strong\u003e25 multiple-dose vials per pack\u003cbr\u003e\u003cstrong\u003eConcentration: \u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLidocaine Hydrochloride 1% (10 mg\/mL)\u003c\/li\u003e\n\u003cli\u003eEpinephrine 1:100,000 (0.01 mg\/mL)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eUse: \u003c\/strong\u003eIndicated for local infiltration anesthesia, peripheral nerve blocks, and various other types of regional anesthesia\u003cbr\u003eVasoconstrictive Action: The presence of epinephrine helps to control bleeding and keeps the anesthetic localized, increasing the duration of action\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanism of Action:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLidocaine: Works by binding and inhibiting voltage-gated sodium channels in the nerve cells, preventing the initiation and propagation of nerve impulses. This leads to a reversible loss of sensation in the targeted area.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eEpinephrine: Acts as a vasoconstrictor by stimulating alpha-adrenergic receptors, which reduces blood flow in the area of injection. This prolongs the duration of action of lidocaine by decreasing its absorption rate into the bloodstream and also helps reduce local bleeding, providing a clearer surgical field.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergies: \u003c\/strong\u003eContraindicated in individuals with a known hypersensitivity to lidocaine, epinephrine, or other amide-type local anesthetics.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystemic Toxicity:\u003c\/strong\u003e Caution is advised to avoid overdosage or unintentional intravascular injection which may result in systemic toxic effects, including CNS disturbances (seizures) or cardiovascular effects (arrhythmias).\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiovascular Health:\u003c\/strong\u003e Use with caution in patients with severe heart disease, arrhythmias, or hyperthyroidism because epinephrine can exacerbate these conditions by increasing heart rate and blood pressure.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProper Administration Techniques: \u003c\/strong\u003eEnsure to aspirate before injecting to avoid intravascular administration. Limit the total lidocaine dose and consider patient-specific factors (e.g., weight, age, comorbid conditions).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSide Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePotential side effects associated with Lidocaine 1% with Epinephrine Injection can include:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eLocal Reactions:\u003c\/strong\u003e Pain, swelling, or redness at the injection site\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCentral Nervous System Effects:\u003c\/strong\u003e Lightheadedness, dizziness, or in rare cases, confusion or seizures at toxic levels\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiovascular Effects:\u003c\/strong\u003e Increased heart rate, hypertension, palpitations, or arrhythmias, primarily due to the epinephrine component\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergic Reactions:\u003c\/strong\u003e Though rare, signs may include rash, itching, or more severe reactions such as anaphylaxis\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOthers: \u003c\/strong\u003eNumbness or tingling which generally subsides as the anesthetic effect diminishes\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIt is essential for administration to be performed by experienced healthcare professionals to manage anesthesia safely, monitoring for potential adverse effects, and employing proper dosing protocols tailored to the patient's individual medical profile.\u003cbr\u003e\u003c\/p\u003e","brand":"Pfizer Injectables","offers":[{"title":"Default Title","offer_id":53337444614462,"sku":"0409-3178-02","price":48822.99,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0872\/3408\/5182\/files\/LidocaineHCL1andEpinephrine11-100000forInjection30mMultipleDose.jpg?v=1776770380","url":"https:\/\/himkhand.com\/products\/lidocaine-hcl-1-and-epinephrine-1-1-100-000-for-injection-30-ml-multiple-dose-25-pack","provider":"Himkhand","version":"1.0","type":"link"}