{"product_id":"lido-2-and-epine","title":"Lidocaine Hydrochloride 2% and Epinephrine 1:200,000 for Injection 20 mL, 5\/Box (Rx) Exp 12\/31\/26","description":"\u003cp\u003eLidocaine Hydrochloride 2% and Epinephrine 1:200,000 is used as a local anesthetic to provide pain relief and reduce bleeding during surgical and dental procedures. Lidocaine blocks nerve impulses to numb the treatment area, while epinephrine constricts blood vessels, prolonging the anesthetic effect and minimizing bleeding. This combination enhances the effectiveness of the anesthesia and improves surgical visibility by managing blood flow, making it ideal for precision-based procedures that require extended anesthesia duration.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline; color: rgb(255, 42, 0);\"\u003e\u003cem\u003e\u003cstrong\u003eCURRENT EXPIRATION FROM MFG : 12\/31\/26 \u003c\/strong\u003e\u003c\/em\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eLidocaine Hydrochloride 2% and Epinephrine 1:200,000 Injection is a combined formulation used for local or regional anesthesia during surgical, dental, or diagnostic procedures. It contains lidocaine to provide analgesic effects and epinephrine as a vasoconstrictor to prolong the anesthetic action and minimize bleeding. This product is supplied in 20 mL vials and packaged by Pfizer Injectables in boxes containing 5 vials.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDetails and Features:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVolume: \u003c\/strong\u003e20 mL per vial\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e Lidocaine Hydrochloride 2% (20 mg\/mL) and Epinephrine 1:200,000 (0.005 mg\/mL)\u003cbr\u003e\u003cstrong\u003ePackaging: \u003c\/strong\u003e5 vials per box\u003cbr\u003e\u003cstrong\u003ePreservative:\u003c\/strong\u003e Multi-dose vials may have preservatives to inhibit microbial growth\u003cbr\u003e\u003cstrong\u003eUse:\u003c\/strong\u003e Local and regional anesthesia for minor surgical or medical procedures\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanism of Action:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLidocaine:\u003c\/strong\u003e Works by blocking sodium ion channels in neuronal cell membranes, preventing the initiation and conduction of nerve impulses. This action provides local anesthesia, creating a loss of sensation in the area where it is applied.\u003cbr\u003e  \u003cbr\u003e\u003cstrong\u003eEpinephrine:\u003c\/strong\u003e Acts as a vasoconstrictor, narrowing blood vessels and reducing local blood flow. This prolongs the action of lidocaine by slowing its absorption into the systemic circulation, enhances the local anesthetic effect, and minimizes bleeding in the surgical field.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergic Reactions:\u003c\/strong\u003e Contraindicated in patients with known allergies to lidocaine, epinephrine, or similar amide-type local anesthetics.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystemic Toxicity:\u003c\/strong\u003e Risk of systemic toxicity increases with excessive dosage or accidental intravascular injection, presenting risks such as CNS disturbances or cardiovascular complications.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiovascular Concerns:\u003c\/strong\u003e Use cautiously in patients with cardiovascular disease, hyperthyroidism, or severe hypertension due to potential exacerbation of symptoms from epinephrine.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProper Administration: \u003c\/strong\u003eEnsure correct administration and avoid intravascular injection by using aspiration techniques before injection.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecial Populations:\u003c\/strong\u003e Adjust dosage for patients with hepatic disease, cardiac impairment, or in elderly and debilitated individuals to prevent accumulation and toxicity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSide Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eLocal Reactions:\u003c\/strong\u003e Possible pain or irritation at the site of injection; rare cases of localized tissue reaction.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCentral Nervous System Effects:\u003c\/strong\u003e Dizziness, restlessness, excitement, or if toxic levels are reached, tremors, convulsions, or CNS depression.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiovascular Effects:\u003c\/strong\u003e Increased heart rate, palpitations, hypertension, or arrhythmias primarily due to epinephrine action.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergic Reactions\u003c\/strong\u003e: Rare but can occur, leading to symptoms ranging from mild rashes to more severe anaphylactic reactions in sensitive individuals.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe use of Lidocaine Hydrochloride 2% with Epinephrine must be managed by healthcare professionals skilled in local anesthetic techniques, ensuring patient safety through proper dosing, administration, and monitoring, along with being prepared to manage potential adverse effects.\u003cbr\u003e\u003c\/p\u003e","brand":"Pfizer Injectables","offers":[{"title":"Default Title","offer_id":53337447727422,"sku":"0409-3183-01","price":4602.99,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0872\/3408\/5182\/files\/Lidocaine-Hydrochloride-2-and-Epinephrine-20-ml-Pfizer-Injectables.jpg?v=1776770456","url":"https:\/\/himkhand.com\/products\/lido-2-and-epine","provider":"Himkhand","version":"1.0","type":"link"}