{"product_id":"hikma-dopamine-hydrochloride-for-injection-40-mg-ml-single-dose-vials-5-ml-25-box","title":"Dopamine Hydrochloride Injection 200 mg\/ Per 5 mL (40 mg\/mL) Single-Dose Vials 5 mL, 25\/Box (Rx)","description":"\u003cp\u003eDopamine Hydrochloride Injection 200 mg\/5 mL is used as an inotropic agent to treat various types of shock, including cardiogenic and septic shock, by improving heart function and blood flow. It stimulates dopaminergic and adrenergic receptors, increasing cardiac output, enhancing renal perfusion, and elevating blood pressure. This medication is administered intravenously in critical care settings to stabilize hemodynamics and support cardiovascular function in acutely ill patients.\u003c\/p\u003e\n\u003cp\u003eDopamine Hydrochloride Injection is a cardiovascular medication used to treat hemodynamic imbalances present in shock syndromes due to myocardial infarctions, trauma, endotoxic septicemia, open-heart surgery, renal failure, and chronic cardiac decompensation. It is indicated for increased cardiac output, raised blood pressure, and improved renal flow and urine output. This formulation by Hikma Injectables comes in single-dose vials with a concentration of 200 mg per 5 mL (40 mg\/mL), packaged in boxes containing 25 vials.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDetails and Features\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eActive Ingredient\u003c\/strong\u003e: Dopamine Hydrochloride\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 40 mg\/mL\u003cbr\u003e\u003cstrong\u003eVolume: \u003c\/strong\u003e5 mL per vial\u003cbr\u003e\u003cstrong\u003ePackaging:\u003c\/strong\u003e 25 single-dose vials per box\u003cbr\u003e\u003cstrong\u003eUse: \u003c\/strong\u003eIV administration for the treatment of shock states\u003cbr\u003e\u003cstrong\u003eManufacturer:\u003c\/strong\u003e Hikma Injectables\u003cbr\u003e\u003cstrong\u003ePurpose: \u003c\/strong\u003ePrimarily used to enhance perfusion to vital organs by improving cardiac output, blood pressure, and urine output\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanism of Action\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDopamine serves as a sympathomimetic agent working by stimulating dopaminergic and adrenergic receptors. Its mechanism is dose-dependent:\u003c\/p\u003e\n\u003cp\u003eLow doses primarily stimulate dopaminergic receptors, promoting vasodilation and increased renal blood flow, leading to enhanced urine output.\u003cbr\u003eIntermediate doses have a predominant effect on β1-adrenergic receptors in the heart, increasing cardiac output.\u003cbr\u003eHigh doses primarily stimulate α-adrenergic receptors, leading to vasoconstriction and increased systemic vascular resistance, thus raising blood pressure.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiovascular Effects:\u003c\/strong\u003e Continuous monitoring of cardiac rhythm, blood pressure, and urine output is essential. Avoid use in patients with pheochromocytoma or uncorrected tachyarrhythmias.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePeripheral Ischemia:\u003c\/strong\u003e High doses or prolonged use can lead to vasoconstriction causing tissue ischemia, particularly in extremities.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypovolemia: \u003c\/strong\u003eCorrect any underlying hypovolemia with appropriate volume expanders before dopamine administration. Interaction with MAO Inhibitors: May potentiate the effects of dopamine; dose adjustments are needed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eSide Effects\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCommon Side Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTachycardia\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003ePalpitations\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eHeadache\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eNausea or vomiting\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSerious Side Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eArrhythmias or exacerbation of existing arrhythmias\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eHypertension or severe hypotension\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003ePeripheral ischemia or gangrene from prolonged high-dose infusion\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003ePolyuria due to increased renal perfusion\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdministration and Monitoring\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDopamine Hydrochloride Injection should be administered intravenously via an infusion pump for accurate control of dosing. Healthcare providers must ensure constant monitoring of vital signs, particularly heart rate and blood pressure, during infusion. Adjustments in dosing should be made based on the therapeutic response and any side effects. Close attention should be given to patients with compromised cardiovascular status and any sudden changes in rhythm should prompt reevaluation of therapy.\u003cbr\u003e\u003c\/p\u003e","brand":"Hikma Injectables","offers":[{"title":"Default Title","offer_id":53335176577342,"sku":"00143-9252-25","price":13013.99,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0872\/3408\/5182\/files\/Dopamine-Hydrochloride-Injection-Vial-25-Per-Box.jpg?v=1776752882","url":"https:\/\/himkhand.com\/products\/hikma-dopamine-hydrochloride-for-injection-40-mg-ml-single-dose-vials-5-ml-25-box","provider":"Himkhand","version":"1.0","type":"link"}