{"product_id":"diltiazem-hydrochloride-for-injection-5-ml-single-dose-vials-10-box-hikma","title":"Diltiazem Hydrochloride Injection 25 mg Per 5 mL Single-dose Vials 10\/Box by Hikma (Rx) *Refrigerated Item*","description":"\u003cp\u003eDiltiazem Hydrochloride Injection is a medication used to manage certain heart conditions, specifically to control rapid heart rates in atrial fibrillation, atrial flutter, and paroxysmal supraventricular tachycardia (PSVT). It functions as a calcium channel blocker, helping to relax the heart muscles and blood vessels, thereby reducing heart rate and improving blood flow. Essential in emergency and critical care, it restores normal heart rhythm and alleviates symptoms related to abnormal cardiac activity.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #ff2a00;\"\u003e\u003cstrong\u003eThis item must be refrigerated and will ship next day air. \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #ff2a00;\"\u003e\u003cstrong\u003eItem ships Signature Required, customer must be available to receive the item.  \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eDiltiazem is a calcium channel blocker that predominately binds to L-type calcium channels in the heart. It inhibits the influx of calcium ions during membrane depolarization, causing significant reduction in myocardial contractility. By slowing the conduction and extension of certain electrical signals, it effectively diminishes atrioventricular node conduction. This results in decelerated heart rate and alleviated cardiac workload, making it highly effective in arrhythmia and angina management.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypotension Risk:\u003c\/strong\u003e Can cause a significant drop in blood pressure; close monitoring of blood pressure is critical during administration.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBradycardia and AV Block:\u003c\/strong\u003e Potential for induction of bradycardia or exacerbation of AV block; caution advised in patients with pre-existing conduction abnormalities.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeart Failure Considerations:\u003c\/strong\u003e Use cautiously in cases of impaired ventricular function.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContraindications:\u003c\/strong\u003e Not advised in patients with hypersensitivity to diltiazem, severe hypotension, sick sinus syndrome or second- or third-degree AV block without a pacemaker, or acute myocardial infarction and pulmonary congestion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eSide Effects:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiovascular Effects:\u003c\/strong\u003e Bradycardia, hypotension, and possible exacerbation of heart failure.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCentral Nervous System: \u003c\/strong\u003eDizziness, headache, or lightheadedness may occur.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGastrointestinal:\u003c\/strong\u003e Nausea or constipation can occur occasionally.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInjection Site Reactions:\u003c\/strong\u003e Local irritation or pain at the site of injection might be observed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eClinical Considerations:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMonitoring:\u003c\/strong\u003e Continuous monitoring of ECG and blood pressure is recommended during administration to ensure patient safety and effective response to treatment.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePatient Assessment: \u003c\/strong\u003eAssess for any history of cardiac conduction abnormalities and ensure conscientious patient history review to avoid contraindications.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDosage and Administration:\u003c\/strong\u003e Administer with accuracy, and consider adjusting the dosage based on the individual patient’s clinical response and tolerability.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe Diltiazem Hydrochloride Injection by Hikma injectables is tailored for health care professionals specializing in cardiology and emergency medicine, providing them with a robust tool for effective acute arrhythmia management. Healthcare providers are urged to consult the full prescribing information and incorporate professional judgment in therapeutic decision-making.\u003cbr\u003e\u003c\/p\u003e","brand":"Himka Injectables","offers":[{"title":"Default Title","offer_id":53335166910782,"sku":"00641-6013-10","price":8275.99,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0872\/3408\/5182\/files\/Diltiazem-Hydrochloride-Injection-25-mg-byHimka-Injectables.jpg?v=1776752723","url":"https:\/\/himkhand.com\/products\/diltiazem-hydrochloride-for-injection-5-ml-single-dose-vials-10-box-hikma","provider":"Himkhand","version":"1.0","type":"link"}