{"product_id":"cathflo-activase-alteplase-powder-vial-2-mg-rx","title":"Cathflo Activase (alteplase) Powder Vial 2 mg (RX)","description":"\u003cp\u003eCathflo Activase (alteplase) is a thrombolytic medication used to restore the function of central venous access devices by dissolving blood clots. Primarily utilized in catheter occlusion, it directly breaks down fibrin within the clot, rapidly improving blood flow and device patency. This enhances treatment efficacy for patients receiving intravenous therapies. Cathflo Activase plays a critical role in maintaining venous access in patients, thereby reducing the risk of complications associated with blocked catheters and ensuring the continuity of essential medical treatments.\u003c\/p\u003e\n\u003cp\u003eThe Cathflo Activase (alteplase) Powder Vial 2 mg is an industry-leading thrombolytic agent manufactured by Genentech USA, designed meticulously for restoring functionality in dysfunctional central venous access devices (CVADs) by clearing obstructive thrombosis. With a sterling reputation in the medical community, Cathflo Activase embodies a reliable solution with a legacy of excellence in patient care, specifically backed by robust science and innovative technology.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details and Features:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eActive Ingredient:\u003c\/strong\u003e Alteplase, a well-verified fibrinolytic enzyme.\u003cbr\u003e\u003cstrong\u003ePresentation: \u003c\/strong\u003eSingle-use vials containing 2 mg of sterile alteplase lyophilized powder.\u003cbr\u003e\u003cstrong\u003eFormulation Excellence: \u003c\/strong\u003eLyophilized powder enables stability and rapid reconstitution, ensuring instant therapeutic application.\u003cbr\u003e\u003cstrong\u003eManufacturer: \u003c\/strong\u003eGenentech USA, a name synonymous with innovation and precision in biotechnology.\u003cbr\u003e\u003cstrong\u003eTarget Use:\u003c\/strong\u003e Specifically engineered for the restoration of patency to central venous access devices obstructed by blood clots.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanism of Action:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCathflo Activase exerts its therapeutic effects through adept catalyzation of the conversion of plasminogen to plasmin, which is a pivotal enzyme in fibrin breakdown. By fostering the dissolution of thrombotic occlusions, alteplase rejuvenates the patency of CVADs with efficacy, preventing line replacements and improving patient outcomes across clinical settings. By targeting fibrin specifically, Cathflo achieves high precision in clot breakdown while sparing other systemic components.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for Use:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e1. Reconstitution: \u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eReconstitute the vial with 2.2 mL of Sterile Water for Injection to obtain a final solution concentration of 1 mg\/mL. Gently swirl until dissolved; do not shake.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e2. Administration:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eWithdraw the reconstituted solution into a syringe.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eInstill up to 2 mg of the reconstituted alteplase solution into the occluded CVAD (volume should not exceed 2 mL).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e3. In-Dwell Time:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAllow the solution to dwell in the catheter for up to 30 minutes. Assess catheter function by attempting to aspirate the contents.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eIf patency is not restored, a second 30-minute dwell can be attempted. \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eConfirm catheter function through flow restoration or aspirating blood.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eContraindications:\u003c\/strong\u003e Do not use in patients with known hypersensitivity to alteplase or any component of the formulation.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBleeding Risk:\u003c\/strong\u003e Exercise caution in patients with coagulopathies, recent surgery, or active internal bleeding.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExclusions:\u003c\/strong\u003e Not intended for systemic infusion to treat coronary or pulmonary thrombi.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHandling:\u003c\/strong\u003e Handle with sterile techniques to prevent contamination and potential complications.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSide Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSerious Reaction:\u003c\/strong\u003e Anaphylactic reaction, though rare, requires immediate cessation of the treatment and administration of appropriate medical therapy.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLocal Bleeding:\u003c\/strong\u003e Some patients may experience minor bleeding at the catheter site.\u003cbr\u003eSystemic Bleeding: Carefully investigate any unexpected bleeding.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCathflo Activase embodies a product that harmonizes safety, effectiveness, and function. Swiftly resolving obstructions in CVADs, it contributes vastly to less invasive and patient-friendly healthcare, focusing on improving well-being and procedural success rates. Always consult healthcare professionals for patient-specific recommendations before adopting new thrombolytic treatments.\u003c\/p\u003e","brand":"Genentech USA","offers":[{"title":"Default Title","offer_id":53335102292286,"sku":"50242-0041-64","price":27893.99,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0872\/3408\/5182\/files\/Cathflo-Activase-_alteplase_-Powder-Vial-2-mg.jpg?v=1776751059","url":"https:\/\/himkhand.com\/products\/cathflo-activase-alteplase-powder-vial-2-mg-rx","provider":"Himkhand","version":"1.0","type":"link"}