{"product_id":"bupivacaine-hydrochloride-for-injection-0-75-single-dose-vials-30-ml-x-25-tray","title":"Bupivacaine 0.75% for Injection Single-Dose Vials 30 mL, 25\/Tray (Rx)","description":"\u003cp\u003eBupivacaine 0.75% for Injection is a local anesthetic used to provide prolonged pain relief by blocking nerve signals during surgical, dental, or obstetric procedures, including labor and delivery. It works by numbing a specific area to inhibit sensation and reduce discomfort. Bupivacaine is particularly effective for regional anesthesia techniques like epidurals and nerve blocks, offering sustained pain management for complex procedures and postoperative recovery.\u003c\/p\u003e\n\u003cp\u003eBupivacaine 0.75% for Injection is a local anesthetic used primarily for regional anesthesia, including epidural and peripheral nerve block techniques. Offered by Pfizer Injectables, these vials are designed for single-dose use in medical settings to provide long-lasting pain relief during surgery or obstetric procedures.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDetails and Features\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eActive Ingredient: Bupivacaine Hydrochloride\u003cbr\u003eConcentration: 0.75% (7.5 mg\/mL)\u003cbr\u003eVolume: 30 mL per vial\u003cbr\u003eFormat: Single-dose vial \u003cbr\u003ePackaging: 25 vials per tray\u003cbr\u003eIndications: Suitable for surgical anesthesia, obstetrical procedures, and other interventions requiring prolonged local or regional anesthetic effect.\u003cbr\u003eManufacturer: Pfizer Injectables\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanism of Action\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBupivacaine works by blocking sodium channels on neuronal membranes, specifically inhibiting the initiation and transmission of nerve impulses. This action results in a reversible loss of sensation, providing effective local or regional anesthesia. Compared to other local anesthetics, bupivacaine has a longer duration of action, making it suitable for procedures requiring extended anesthesia.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiovascular Risks:\u003c\/strong\u003e There is a significant risk of cardiotoxicity, especially if inadvertently injected intravascularly. This includes the potential for arrhythmias or cardiac arrest. \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCentral Nervous System Effects:\u003c\/strong\u003e Potential for CNS toxicity, which may present as tinnitus, seizures, or respiratory depression.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergic Reactions:\u003c\/strong\u003e Though rare, patients may exhibit hypersensitivity to amide-type anesthetics.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUse in Pregnant Women: \u003c\/strong\u003eCaution is advised, particularly when used for epidural anesthesia, as it can affect maternal blood pressure and fetal wellbeing.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContraindications:\u003c\/strong\u003e Not suitable for intravenous regional anesthesia (Bier block) or in patients with any history of hypersensitivity to bupivacaine or similar drugs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eSide Effects\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCommon Side Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eProlonged numbness or tingling in the area of injection\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eHypotension\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eNausea\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eDizziness or lightheadedness\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSerious Side Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiovascular events:\u003c\/strong\u003e Bradycardia, hypotension, cardiac arrest\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCentral nervous system toxicity:\u003c\/strong\u003e Seizures, confusion, persistent drowsiness\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergic reactions\u003c\/strong\u003e: Anaphylaxis, rash, or hives\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRespiratory depression\u003c\/strong\u003e or difficulty breathing\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdministration and Monitoring\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAdministration should be conducted by trained healthcare professionals familiar with anesthesia techniques and the management of potential toxicities. It is essential to monitor cardiovascular and respiratory function throughout the use of bupivacaine, especially when used in high doses or in sensitive populations. Facilities for resuscitation should be readily available when using this medication. Adjustments in dosage and careful monitoring are crucial to mitigate adverse effects, especially in patients with existing cardiac conditions or those receiving other CNS depressants.\u003cbr\u003e\u003c\/p\u003e","brand":"Pfizer Injectables","offers":[{"title":"Default Title","offer_id":53335090430270,"sku":"00409-1165-02","price":18319.99,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0872\/3408\/5182\/files\/Pfizer--0409-1165-02-Bupivacaine-Hydrochloride-Injection-USP.jpg?v=1776750770","url":"https:\/\/himkhand.com\/products\/bupivacaine-hydrochloride-for-injection-0-75-single-dose-vials-30-ml-x-25-tray","provider":"Himkhand","version":"1.0","type":"link"}