{"product_id":"amphotericin-b-for-injection-50-mg-vial-for-intravenous-infusion-only-refrigerated-product-rx","title":"Amphotericin B Injection 50 mg Vial For Intravenous Infusion Only **Refrigerated (RX)","description":"\u003cp\u003eAmphotericin B for Injection 50 mg is an antifungal medication used to treat serious fungal infections. It targets severe systemic infections by binding to fungal cell membranes, causing cell death. This effective treatment is often employed for life-threatening conditions like aspergillosis, candidiasis, and mucormycosis. Amphotericin B is administered intravenously in a clinical setting, due to its potential for significant side effects and the necessity for careful monitoring by healthcare professionals.\u003c\/p\u003e\n\u003cp\u003eIntroducing Amphotericin B for Injection, a premier antifungal medication offered by Xgen Pharma, designed to provide effective treatment against severe fungal infections. With a longstanding reputation for its potent antifungal properties, Amphotericin B remains a critical choice in the management of systemic mycoses and a cornerstone for healthcare professionals worldwide.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details and Features\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Name:\u003c\/strong\u003e Amphotericin B for Injection\u003cbr\u003e\u003cstrong\u003eStrength:\u003c\/strong\u003e 50 mg per vial\u003cbr\u003e\u003cstrong\u003eManufacturer: \u003c\/strong\u003eXgen Pharma\u003cbr\u003e\u003cstrong\u003eDosage Form:\u003c\/strong\u003e Lyophilized powder for intravenous use\u003cbr\u003e\u003cstrong\u003ePackaging: \u003c\/strong\u003eAvailable in a sterile vial for reconstitution\u003cbr\u003e\u003cstrong\u003eIndications:\u003c\/strong\u003e Indicated for the treatment of systemic fungal infections such as cryptococcal meningitis, aspergillosis, candidiasis, histoplasmosis, and leishmaniasis, among others.\u003cbr\u003e\u003cstrong\u003eStorage Conditions:\u003c\/strong\u003e Store at temperatures between 2°C to 8°C (36°F to 46°F) and protect from light.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFeatures\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBroad-spectrum Efficacy: \u003c\/strong\u003eEffective against a wide range of pathogenic yeasts and molds.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGold Standard Antifungal:\u003c\/strong\u003e Considered the treatment of choice for life-threatening systemic fungal infections.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProven Track Record:\u003c\/strong\u003e Well-established with decades of clinical use and research.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpert Manufacture:\u003c\/strong\u003e Produced with precision by Xgen Pharma, guaranteeing quality and reliability.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMechanism of Action\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAmphotericin B targets fungal cell membranes. It binds to ergosterol, a vital component of fungal cell membranes, thereby creating pores in the cell membrane. This leads to increased membrane permeability, allowing essential ions like potassium and other molecules to leak out. The resultant loss of cellular contents causes cell death, making Amphotericin B a powerful fungicidal agent against a variety of fungi.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for Use\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e1. Reconstitution: \u003c\/strong\u003eTo reconstitute, aseptically add 10 mL of Sterile Water for Injection to the vial containing 50 mg of Amphotericin B, resulting in a concentration of 5 mg\/mL. Gently shake to ensure complete dissolution.\u003cbr\u003e\u003cstrong\u003e2. Dilution:\u003c\/strong\u003e Further dilute the reconstituted solution in 500 mL of 5% Dextrose Injection to attain a concentration in the range of 0.1 mg\/mL to 0.25 mg\/mL before administration.\u003cbr\u003e\u003cstrong\u003e3. Administration: \u003c\/strong\u003eAdminister intravenously over a period of 2 to 6 hours. The rate of infusion may be adjusted according to patient tolerance.\u003cbr\u003e\u003cstrong\u003e4. Dosage: \u003c\/strong\u003eThe specific requirements for dosage will depend on the type, severity of infection, and patient’s condition. Initiate treatment under the supervision of a qualified healthcare professional.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRenal Impairment:\u003c\/strong\u003e Use with caution in patients with preexisting renal damage or impairment. Regular monitoring of renal function is advised.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInfusion Reactions:\u003c\/strong\u003e Patients may experience acute infusion-related reactions such as fever, chills, or headache. Pre-treat with antipyretics or antihistamines if necessary.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMonitor Electrolytes:\u003c\/strong\u003e Potential for hypokalemia and hypomagnesemia. Monitor and adjust electrolyte levels as needed.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interactions:\u003c\/strong\u003e May interact with other nephrotoxic agents or medications affecting electrolyte balance.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eSide Effects\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eThe use of Amphotericin B can lead to side effects in some patients. Notable potential side effects include:\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eInfusion-related Symptoms:\u003c\/strong\u003e Fever, chills, nausea, vomiting, and muscle or joint pain.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNephrotoxicity: \u003c\/strong\u003eRenal impairment may occur, leading to increased blood urea and creatinine levels.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte Imbalance:\u003c\/strong\u003e Hypokalemia (low potassium levels) and hypomagnesemia (low magnesium levels).\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnemia:\u003c\/strong\u003e Occasional reports of anemia with prolonged usage.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHepatic Dysfunction:\u003c\/strong\u003e Possible liver enzyme elevation. \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAlways discuss with a healthcare professional before starting any new medication. Adherence to recommended treatment guidelines and continuous monitoring will help mitigate potential risks.\u003c\/p\u003e\n\u003cp\u003eFor comprehensive treatment consideration, trust Amphotericin B for Injection by Xgen Pharma – your definitive choice for combating serious fungal infections.\u003c\/p\u003e","brand":"Xgen Pharma","offers":[{"title":"Default Title","offer_id":53335040131390,"sku":"39822-1055-05","price":16273.99,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0872\/3408\/5182\/files\/Amphotericin-B-50-mg-Antifungal-Infection-Treatment.jpg?v=1776749228","url":"https:\/\/himkhand.com\/products\/amphotericin-b-for-injection-50-mg-vial-for-intravenous-infusion-only-refrigerated-product-rx","provider":"Himkhand","version":"1.0","type":"link"}