{"product_id":"ambisome-amphotericin-b-liposome-50-mg-per-vial-single-dose-vial-20-ml-rx","title":"Ambisome Amphotericin B Liposome 50 mg Per Vial SIngle-Dose Vial 20 mL *Refrigerated (RX)","description":"\u003cp\u003eAmbisome (Amphotericin B Liposome) 50 mg Vial is an antifungal medication used to treat severe and potentially life-threatening fungal infections, such as aspergillosis, candidiasis, and cryptococcal meningitis. The liposomal formulation enhances the drug’s delivery, improving efficacy while minimizing the renal toxicity typically associated with conventional amphotericin B. Ambisome is often used in patients with weakened immune systems, including those undergoing chemotherapy or organ transplants. It is administered intravenously in a hospital setting to ensure close monitoring.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cem\u003e\u003cstrong\u003e *** Refrigerated Item, Ships Next Day Air, Signature Required ***\u003c\/strong\u003e\u003c\/em\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eAmbisome® (Amphotericin B Liposome for Injection) by Astellas Pharma presents a revolutionary advancement in antifungal therapy. Designed to combat severe and potentially life-threatening fungal infections, Ambisome offers the powerful efficacy of amphotericin B in a liposomal formulation. This innovation enhances drug delivery while minimizing toxicity, making it a preferred choice among healthcare professionals. Packaged in convenient 50 mg single-dose vials, Ambisome requires refrigeration to maintain its stability and potency until use.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details and Features:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eConcentration and Packaging:\u003c\/strong\u003e Each vial contains 50 mg of amphotericin B encapsulated in a liposomal delivery system. Available in a single-dose 20 mL vial format.\u003cbr\u003e\u003cstrong\u003eStorage Requirements: \u003c\/strong\u003eMust be stored refrigerated to preserve the integrity of the liposomal encapsulation and maintain drug efficacy.\u003cbr\u003e\u003cstrong\u003eBrand: \u003c\/strong\u003eDeveloped and manufactured by Astellas Pharma, a leader in global healthcare solutions committed to innovative treatments.\u003cbr\u003e\u003cstrong\u003eFormulation Benefits:\u003c\/strong\u003e The liposomal delivery system significantly reduces the nephrotoxicity and infusion-related reactions commonly associated with conventional amphotericin B.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanism of Action:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAmbisome works by binding to ergosterol, a crucial component of fungal cell membranes, disrupting membrane integrity and leading to cell death. The liposomal formulation allows targeted delivery of amphotericin B to fungal cells, while sparing human cells, thereby enhancing therapeutic benefits and reducing toxicity. Liposomes also enable prolonged circulation time in the bloodstream, increasing drug availability at infection sites.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDirections:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDosage and Administration\u003c\/strong\u003e: Administer under the guidance of a qualified healthcare professional. Dosage varies based on the type and severity of the infection and patient response. Typically, Ambisome is administered intravenously.\u003cbr\u003e\u003cstrong\u003eReconstitution:\u003c\/strong\u003e Follow specific guidelines for reconstituting and diluting the drug before infusion. Use aseptic techniques to ensure sterility.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eInfusion-Related Reactions:\u003c\/strong\u003e Monitor patients closely during administration for any infusion-related reactions, which may include fever, chills, or rigors.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRenal Impairment:\u003c\/strong\u003e Ambisome has lower nephrotoxicity than traditional formulations, but caution is advised in patients with pre-existing renal impairment.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnaphylaxis and Immune Precautions\u003c\/strong\u003e: There is a risk of anaphylactic reactions; ensure resuscitation equipment is available.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePregnancy and Breastfeeding:\u003c\/strong\u003e Use only if the potential benefits justify the potential risk to the fetus or infant. Consult healthcare professionals when prescribing for pregnant or breastfeeding women.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eSide Effects:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCommon Effects:\u003c\/strong\u003e Fever, chills, hypokalemia (low potassium), and elevated serum creatinine levels may occur.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSerious Effects:\u003c\/strong\u003e Although rare, serious side effects can include nephrotoxicity, anaphylactic reactions, and severe infusion-related reactions.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLess Common:\u003c\/strong\u003e Abnormal liver function tests, headache, and nausea may be observed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAmbisome by Astellas Pharma represents a significant advancement in the treatment of serious fungal infections, blending efficacy with improved safety through its liposomal encapsulation. Trust in Ambisome for reliable, compassionate care in antifungal therapy, backed by the pioneering reputation of Astellas Pharma.\u003c\/p\u003e","brand":"Astellas Pharma Branded","offers":[{"title":"Default Title","offer_id":53335034888510,"sku":"00469-3051-30","price":45474.99,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0872\/3408\/5182\/files\/Ambisome-Amphotericin-B-Liposome-50-mg-by-Gilead.jpg?v=1776749132","url":"https:\/\/himkhand.com\/products\/ambisome-amphotericin-b-liposome-50-mg-per-vial-single-dose-vial-20-ml-rx","provider":"Himkhand","version":"1.0","type":"link"}